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Iopromide

  • Name Iopromide
  • CAS 73334-07-3
  • Purity 99%
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Product Details

Quality Factory Supply 99% Pure Iopromide 73334-07-3 with Efficient Delivery

  • Molecular Formula: C18H24I3N3O8
  • Molecular Weight: 791.117
  • Appearance/Colour: off-white to white powder 
  • Vapor Pressure: 5E-30mmHg at 25°C 
  • Melting Point: broad (160oC transition) 
  • Refractive Index: 1.709 
  • Boiling Point: 840.9 °C at 760 mmHg 
  • PKA: 10.62±0.70(Predicted) 
  • Flash Point: 462.4 °C 
  • PSA: 168.66000 
  • Density: 2.173 g/cm3 
  • LogP: 0.05740 

Iopromide(Cas 73334-07-3) Usage

Definition

ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.

Brand name

Ultravist (Berlex).

General Description

Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.

InChI:InChI=1/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29)

73334-07-3 Relevant articles

Preparation method and application of iopromide intermediate (by machine translation)

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Paragraph 0102-0104, (2020/07/24)

The invention relates to a preparation m...

Preparation method of iopromide

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Paragraph 0043; 0052; 0053; 0054; 0063; 0064, (2019/08/01)

The invention belongs to the technical f...

Preparation methods of iopromide and intermediate of iopromide

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Paragraph 0105-0107, (2018/03/24)

The application of the invention relates...

A method for preparing [...]

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, (2018/12/13)

The present invention relates to an X-ra...

73334-07-3 Process route

5-methoxyacetylamino-2,4,6-triiodoisophthalic acid [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide
1193076-40-2

5-methoxyacetylamino-2,4,6-triiodoisophthalic acid [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide

iopromide
73334-07-3

iopromide

Conditions
Conditions Yield
With water; sodium hydroxide; In N,N-dimethyl acetamide; at 20 - 25 ℃; for 10h;
85%
With water; sodium hydroxide; at 20 - 25 ℃; for 10h; Industry scale;
C<sub>26</sub>H<sub>32</sub>I<sub>3</sub>N<sub>3</sub>O<sub>12</sub>

C26 H32 I3 N3 O12

iopromide
73334-07-3

iopromide

Conditions
Conditions Yield
With sodium methylate; In methanol; at 75 ℃; for 8h;
100%
C26H32I3N3O12; With sodium hydroxide; at 50 ℃; for 4h;
With hydrogenchloride; pH=2-3;
99%

73334-07-3 Upstream products

  • 40137-22-2
    40137-22-2

    3-methylamino-propane-1,2-diol

  • 7440-44-0
    7440-44-0

    pyrographite

  • 1193076-40-2
    1193076-40-2

    5-methoxyacetylamino-2,4,6-triiodoisophthalic acid [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide

  • 1955-46-0
    1955-46-0

    5-nitro-1,3-benzenedicarboxylic acid, monomethyl ester

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